PROPERTIES OF THE ANTIHEMORRHAGIC VITAMIN (VITAMIN K)

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[Vitamin K].

In this paper, highly sensitive methods for measuring of vitamin K in serum, feces and milk are described. Vitamin K1 and the menaquinone family from the serum, feces and milk were separated by high performance liquid chromatography. The separated K1 and menaquinone families were detected by a fluorescence spectrophotometer after their reduction with sodium borohydride or platinum catalyst colu...

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Vitamin K ................................................................................................................................... 1 1 Dietary sources and intake ..................................................................................................... 1 2 Physiology and metabolism ...............................................................................................

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A case report of temporary and acquired vitamin K-dependent clotting factor deficiency without any response to administrated vitamin K

Abstract Background and Objectives Vitamin K-dependent clotting factor deficiency (VKCFD) is usually an acquired problem due to liver disease, malabsorption, and overdose of warfarin.  In the present paper the significance and role of vitamin K-dependent coagulation factors in menorrhagia were evaluated.   Case We present a rare case of 43 year woman with acquired vitamin K deficiency and se...

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Vitamin K: the coagulation vitamin that became omnipotent.

Vitamin K, discovered in the 1930s, functions as cofactor for the posttranslational carboxylation of glutamate residues. Gammacarboxy glutamic acid (Gla)-residues were first identified in prothrombin and coagulation factors in the 1970s; subsequently, extra-hepatic Gla proteins were described, including osteocalcin and matrix Gla protein (MGP). Impairment of the function of osteocalcin and MGP ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1938

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)73961-6